8mg nicotine gum
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Nicotine gum is a type of chewing gum that delivers nicotine to the body. It is used as an aid in nicotine replacement therapy NRT , a process for smoking cessation and quitting smokeless tobacco. The nicotine is delivered to the bloodstream via absorption by the tissues of the mouth. It is currently available over-the-counter in Europe, the US and elsewhere.
The pieces are usually available in individual foil packages and come in various flavors. Nicotine gum can be used in combination with long acting nicotine replacement therapy formulations such as the nicotine patch. It has been shown that combination therapy is more effective than use of a single agent for tobacco cessation. Nicotine absorption from chewing gum is much lower than during smoking. As with other types of addiction, pharmacological therapy is not the only component in treating addiction.
Behavioral habits must also be treated, and modifications to these behaviors along with pharmacological therapies can greatly impact and improve chances of successful tobacco cessation. Although there are many brands of nicotine gum available, they are dosed in a similar manner. The size of nicotine gum is the same for both strengths. Users should not use more than 24 pieces of gum per day.
Nicotine is a vasoconstrictor ; it constricts arteries , which increases the resistance against which the heart has to pump blood, effectively making it harder for the heart to pump blood through the body.
The result is enhanced shear stress on vessel walls, and repeated nicotine exposure contributes to accelerated health problems that are a function of chronic vascular injury such as coronary artery disease , acute cardiac ischemic events, and hypertension [9] Studies have shown that nicotine exposure contributes to stroke , peptic ulcer disease , and esophageal reflux.
Nicotine gum requires frequent periods of chewing throughout the day which can lead to jaw soreness. Two unpleasant symptoms which affect some new users and existing users who make excessive use of nicotine gum, are hiccups [11] and a perceived constriction of the throat muscles, as accidental swallowing of saliva containing high amounts of nicotine may cause irritation.
Women who use nicotine gum and patches during the early stages of pregnancy face an increased risk of having babies with birth defects according to a study that looked at about 77, pregnant women in Denmark. The study found that women who used nicotine-replacement therapy in the first 12 weeks of pregnancy had a greater risk of having babies with birth defects than women who did not. No studies have been done to show the effects of nicotine gum on breast-feeding.
The nicotine from gum will end up in the breast milk. Animal models have shown that nicotine may increase the likelihood of infant death syndrome. It is generally not recommended that breast-feeding mothers use any nicotine products. Because this medication requires frequent periods of chewing throughout the day, people who have Temporomandibular joint disease should avoid using this medication as it will exacerbate their disease.
The nicotine gum should be kept tightly closed in a dry cool place and out of reach of children and pets. Used nicotine gum must be wrapped in paper and put in the trash can. When the medication is no longer needed, do not flush it down the toilet and return it to pharmacies through mail-back service. In case of limited access to mail-back program, see FDA's Safe Disposal of Medicines website for further instructions.
Various policies exist worldwide as to the accessibility of these medications. Originally in the s gum was sold only by prescription. In most of the EU and the US, nicotine gum is currently [update] available at pharmacies over-the-counter subject to the same restrictions on underage purchases as tobacco.
Depending upon jurisdiction and pharmacy the purchaser may be directed to the pharmacist , or nicotine gum may be purchased off-the-shelf.
If sold where tobacco products are also sold, the display of the nicotine therapy products may be adjacent to the tobacco display. Although nicotine gum can be purchased over the counter, in efforts to promote and support tobacco cessation the FDA has approved the nicotine gum, as well as other NRT agents and two other cessation agents: Varenicline and bupropion, for a tobacco cessation indication. This is very important as it enabled prescriptions of these agents to potentially get some coverage based upon your specific insurance plan, leading to potential lower prices than what are seen over the counter.
In New Zealand and now Australia nicotine gum and patches are classified General Sale and can be sold in outlets other than pharmacies, e. This has resulted in a steep fall in the retail price, particularly from online New Zealand stores. Nicotine gum, lozenges and similar preparations can be now readily found on the shelf in the medicinal aisle of most major chain supermarkets and can be purchased alongside other grocery items.
In the United Kingdom many NRT products are available in shops, supermarkets, petrol stations and even schools, although an age limit of 12 is required. Own-brand NRT products are available from some pharmacy chains. From Wikipedia, the free encyclopedia.
The Cochrane Database of Systematic Reviews. Clinical Pharmacology and Therapeutics. Centers for Disease Control and Prevention. Retrieved Nicorette Gum labeling-FDA. Retrieved October 23, Archived from the original on 29 November Retrieved 20 November Smoking habits, nicotine use, and congenital malformations.
Cessation Interventions" PDF. Center for Disease Control. Pharmaceutical Journal. Retrieved 29 May Categories : Smoking cessation Chewing gum. Hidden categories: All articles with dead external links Articles with dead external links from April Articles with permanently dead external links Articles containing potentially dated statements from All articles containing potentially dated statements. Namespaces Article Talk. Views Read Edit View history. By using this site, you agree to the Terms of Use and Privacy Policy.
Nicorette Gum helps calm cravings and reduces anxiety caused by quitting smoking. Try our nicotine gum today and start your quit smoking journey. Nicotine gum carries a category C classification and the nicotine patch is a By combining two pieces of gum, 0, 2, 4, and 8 mg of nicotine were available.
When a nicotine lozenge is placed in the mouth and allowed to dissolve over the course of 20 to 30 minutes, nicotine is absorbed into the bloodstream, relieving short-term cravings to smoke. You cannot smoke while using nicotine lozenges, so many people use them as a quit aid, though there are many things you should know and understand about these lozenges before using them to help you quit smoking. Nicotine lozenges offer smokers trying to quit and ex-smokers quick relief from cravings that are part of nicotine withdrawal.
A boy of 14 collapsed after chewing 45 sticks of nicotine gum - equivalent to Marlboro Light cigarettes - in just 25 minutes.
Nicotine, the primary alkaloid in tobacco products and a naturally occurring autonomous substance, is a nicotine receptor agonist in the peripheral and central nervous systems and has pronounced CNS and cardiovascular effects. The principal mechanism of action of nicotine replacement therapy NRT is to partially replace the nicotine formally obtained from tobacco.
Nicotine gum: dose-related effects on cigarette smoking and subjective ratings.
Chewing gum is a fun pastime and distraction for many people, so researchers got the idea that it could work as a replacement for smoking. Many people chew gum when they are trying to quit smoking because it provides oral gratification similar to a smoking habit. In the s, gum that contains nicotine was introduced and offered by prescription as a method to help people quit smoking. Nicotine gum is a form of smoking cessation aid, which means it is intended to help people stop smoking. It generally works by replacing the nicotine that smokers usually get through tobacco products.
Nicotine gum
Nicotine gum can help you quit smoking, but you need to use it properly — and there is a risk that you could become addicted to the gum itself. Seventy-four percent of Americans who smoke say they would like to give it up , and 67 percent of smokers believe they are addicted to cigarettes, according to a Gallup poll. Although quitting can be a challenge , there are a number of methods that have been proven to help, including medication and counseling. Many people who want to stop smoking turn to nicotine gum, which research shows can be helpful for smokers who are trying to quit but are struggling with nicotine withdrawal. It was the first nicotine replacement therapy to be approved for over-the-counter sale by the U. Food and Drug Administration, which gave it the nod back in February , months before nicotine patches were approved for non-prescription use. Nicotine gum is available under the brand names Nicorette and Nicorette DS. Generic forms of nicotine polacrilex gum are available, under names such as Habitrol, Nicotrol, and Prostep. The gum comes in dosages of 2 and 4 milligrams mg. You can purchase nicotine gum at most drug stores, grocery stores, and department stores.
The effects of nicotine-containing chewing gum on cigarette smoking and subjective and physiological response were evaluated in eight normal volunteers.
Chewing gum is a surprisingly ancient human behaviour, dating back at least 6, years. The ancient greeks even chewed gum with antiseptic properties to freshen their breath! In the s, researchers came up with the clever idea that gum containing nicotine could help people quit smoking. Nicotine gum is a type of nicotine replacement therapy NRT — a group of products designed to provide you with a small amount of nicotine, without the tar and other harmful chemicals found in cigarettes.
Nicotine Gum: A Complete Guide
For people who want to stop smoking, there are many different options available. These include products based on nicotine, the addictive drug that keeps smokers hooked. In each case, they aim to help smokers wean themselves off tobacco by providing a hit of nicotine without any of the other cancer-causing substances found in cigarette smoke. NRT products work by giving less nicotine more slowly and are much less addictive. This week, alarming headlines hit the newspapers claiming that the nicotine in these products could actually cause mouth cancer. But while the results are interesting, this conclusion and many of the news stories based on it are premature. It looked at one specific gene — FOXM1 — and the protein that it encodes. The researchers looked at samples of mouth cells grown in the lab and taken from 75 people, of whom 15 had mouth cancer. They found that high levels of FOXM1 activity were associated with mouth cancer. Compared to normal mouth cells, the gene was more active in those that were on the verge of becoming cancerous, and even more active in those that had actually turned into cancer cells. The researchers then exposed the lab-grown mouth cells to concentrations of nicotine, similar to those that build up in the mouths of people who chew nicotine gum. They found that at these concentrations, nicotine switched on the FOXM1 gene in their cells, and speeded up the transformation of normal cells into cancerous ones.
A complete guide to nicotine gum
Nicotine gum is a type of chewing gum that delivers nicotine to the body. It is used as an aid in nicotine replacement therapy NRT , a process for smoking cessation and quitting smokeless tobacco. The nicotine is delivered to the bloodstream via absorption by the tissues of the mouth. It is currently available over-the-counter in Europe, the US and elsewhere. The pieces are usually available in individual foil packages and come in various flavors. Nicotine gum can be used in combination with long acting nicotine replacement therapy formulations such as the nicotine patch. It has been shown that combination therapy is more effective than use of a single agent for tobacco cessation. Nicotine absorption from chewing gum is much lower than during smoking.
