Hemp supplement
Kama Hemp Juice capsules are a high-quality food supplement that is desired because it contains a broad range of nutrients. MediHemp Organic Hemp Capsules. Hemp Seed Oil. Hemp Face Wash Gel — Hemporium.
Kama Hemp CBDa Capsules
If the address matches an existing account you will receive an email with instructions to reset your password. If the address matches an existing account you will receive an email with instructions to retrieve your username. Hemp is an extraordinary crop, with enormous social and economic value, since it can be used to produce food, textiles, clothing, biodegradable plastics, paper, paint, biofuel, and animal feed, as well as lighting oil.
Various parts of the hemp plant represent a valuable source of food and ingredients for nutritional supplements. While hemp inflorescence is rich in nonpsychoactive, yet biologically active cannabinoids, such as cannabidiol CBD , which exerts potent anxiolytic, spasmolytic, as well as anticonvulsant effects, hempseed has a pleasant nutty taste and represents a valuable source of essential amino acids and fatty acids, minerals, vitamins, and fibers.
In addition, hempseed oil is a source of healthy polyunsaturated fatty acids, and hemp sprouts are rich in antioxidants. This review article aims to provide a comprehensive outlook from a multidisciplinary perspective on the scientific evidence supporting hemp beneficial properties when consumed as food or supplement. Marketing of hemp-derived products is subjected to diversified and complex regulations worldwide for several reasons, including the fact that CBD is also the active principal of pharmaceutical agents and that regulatory bodies in some cases ban Cannabis inflorescence regardless of its THC content.
Some key regulatory aspects of such a complex scenario are also analyzed and discussed in this review article. Cannabis is a genus of flowering plants belonging to the family of Cannabaceae. According to some authors, the Cannabis genus includes three different species, such as Cannabis sativa , C.
Over the past decades, to counteract its widespread use as a recreational drug, the authorities had banned cultivation of any variety of Cannabis without making a distinction based on the THC content, which severely and unfairly harmed the hemp industry. During the past few years most Western countries have recognized the incontrovertible economic, potential, and social value of industrial hemp and even promoted its cultivation through ad hoc legislative interventions, which have established a legal threshold for THC concentration in the dry plant material e.
Hempseeds and inflorescence are extensively used worldwide as source of food and supplement ingredients.
Hemp inflorescence is rich in nonpsychoactive, yet biologically active cannabinoids, such as cannabidiol CBD , which exerts potent anxiolytic, spasmolytic, as well as anticonvulsant effects, among others.
Hemp sprouts can also be consumed as food. Compared to hempseeds, hemp sprouts are characterized by higher content in total polyphenols, flavonoids, and flavonols, known for their positive cardiovascular and metabolic effects. Presently, marketing of CBD-based dietary supplements, which is under intense debate in the scientific community, 18 is differently regulated in the United States, Europe, and the rest of the world.
The aim of this narrative review is to provide a comprehensive analysis of the available scientific evidence on the composition, nutritional properties, as well as safety of hemp consumed as food and nutritional supplements, with a focus on the related complex socioeconomic and regulatory aspects. The extensive research that has probably made Cannabis the most studied plant in human history has allowed to identify hundreds of different compounds with potential biological activity, including more than terpenoids, cannabinoids, 50 hydrocarbons, 34 glycosidic compounds, 27 nitrogenous compounds, 25 noncannabinoid phenols, 22 fatty acids, 21 simple acids, 18 amino acids, 13 simple ketones, 13 simple esters and lactones, 12 simple aldehydes, 11 proteins, glycoproteins, and enzymes, 11 steroids, 9 trace elements, 7 simple alcohols, 2 pigments, as well as vitamin K.
Two recently published studies using an optimized method for chemical characterization of hemp identified lipids, including 52 phospholipids and 80 sulfolipids, 20 and compounds belonging to the classes of flavonoids, proanthocyanidins, and phenolic acids.
The endocannabinoid system is physiologically involved in regulation of appetite, pain, mood, memory, inflammation, insulin sensitivity, as well as fat and energy metabolism, with a wide variety of potential therapeutic implications for treatment of pain, neuropsychiatric disorders, neurological diseases, and inflammatory bowel, which may benefit from CB1 activation, as well as for treatment of obesity, type 2 diabetes, and hepatic or kidney disorders, which may benefit from CB1 antagonism.
CBD is biosynthesized as a carboxylic acid through the same metabolic pathway as THC, with the exception of the last chemical reaction that is catalyzed by CBD acid synthase instead of THC acid synthase.
CBD dose-dependent anticonvulsant activity was also shown in a 4-aminopyridine model prepared using mouse hippocampal brain slices at concentrations ranging from 0. A potent anxiolytic effect of CBD has also been shown in pre-clinical models. Interestingly, CBD spectrum of biological activities includes immune-modulating and anti-inflammatory properties. Clinical activity was accompanied by histologic evidence of diminished axonal damage and microglial activation and by in vitro evidence of decreased T cell proliferation in response to the myelin antigen.
CBD also presents antineoplastic activity shown in several pre-clinical models. TRPA1 is also desensitized by the strong agonistic activity exerted by another cannabinoid lacking psychotropic effects, CBC, which results in a potent anti-inflammatory effect, as shown in a mouse model of colitis induced by dinitrobenzene sulfonic acid. Terpenes found in hemp, which confer the typical aroma and flavor, may also exert multiple biologically relevant effects.
In a mouse model of osteoarthritis, myrcene showed meaningful anti-inflammatory activity in human chondrocytes. In an in vitro study conducted in human eosinophilic leukemia HL clone 15 cells, limonene was capable of inhibiting reactive oxygen species production even at low concentrations 7.
As a plant-derived, easily extractable, biologically active compound with large therapeutic index and overall excellent safety profile, CBD is currently marketed both as a mainly hemp-derived dietary supplement, subjected to evolving legislation and regulatory actions, and as a drug, such as Epidiolex CBD only and Sativex THC and CBD in ratio , with specific approval indications worldwide. Epidiolex is currently both European Medical Agency- and Food and Drug Administration approved against seizures associated with Lennox—Gastaut or Dravet syndrome in patients 2 years of age or older on the grounds of high quality scientific evidence from randomized controlled trials.
The scenario is also confusing in Europe, where CBD-containing products e. Czech Republic and remains currently pending.
In a study involving 88 CBD liquid products, including oil and vaporization liquid, marketed by 31 different companies, CBD median levels were 9.
The widespread use of CBD products has been poorly investigated. One study recruited individuals who participated in an online survey designed to assess the reasons, risks, and modalities behind CBD consumption.
Among the users who reported using CBD to treat a medical condition, which most frequently included pain, anxiety, depression, and sleep disorders, approximately one-third of participants stated that CBD alone could manage their medical condition by itself. Despite its numerous limitations, including the lack of data regarding the dose consumed and timing of consumption, as well as the absence of a control group, this study has the merit to capture consumers' motivations behind CBD use, which is essential to direct further research and investigations, as well as regulatory interventions.
Despite the large consumption of CBD as a nutritional supplement, evidence from pre-clinical and clinical studies exploring the effects of CBD as a dietary ingredient is scarce to nonexisting. This may represent the dose range for testing CBD hemp supplements as part of a healthy diet. The need for further research is becoming more compelling as multinational companies such as Coca-Cola are planning to supplement some of their products with CBD, 64 which will expand the variety of CBD-supplemented food and beverages—as an example, a Californian company is marketing CBD-supplemented wine, 65 while New York-based company Sovereign Vines has produced a wine with special tastes and flavors of hemp.
Hemp has been a valuable source of food for mankind for millennia, as shown by the hempseeds found in tombs dating back to the third millennium before Christ in China, where roasted hempseed can still be bought on the street as snacks. The true seed is an achene, enveloped by a subtle and hard pericarp, and matures 3—6 weeks after the fertilization of female flower. Hempseeds are rich in polyunsaturated fatty acids, which also vary among different genotypes.
Hempseed proteins represent a valuable source of sulfur-containing amino acid methionine and cystine and provide high quantities of arginine, an essential amino acid with beneficial cardiovascular properties. Accumulating evidence supporting the antihypertensive effect of hydrolyzed hempseed proteins, possibly mediated by inhibition of angiotensin-converting enzyme and renin, 71 provided the rationale for an ongoing human trial testing hemp protein powder as an antihypertensive nutritional intervention.
Hempseeds can also be used to make flour and oil with valuable nutritional properties. With its pleasant, nutty-favored taste, with somewhat of a bitter aftertaste, 85 hempseed oil may be used in cooking as a replacement for olive oil, which has established benefits for cardiovascular health. Importantly, consumption of hempseed oil resulted in subjective decreases in both skin dryness and itchiness along with reduced use of topical medications, while this effect was not reported for olive oil.
Although limited, these results suggest that hempseed oil can be part of a diet with potential health advantages. Finally, hemp sprouts may also represent an attractive functional food due to their content in flavonoids and flavanols, 90 although clinical trials exploring palatability and potential benefits associated with their consumption are lacking.
Hemp potential as an extraordinary source of supplement ingredients and a healthy food remains largely to be investigated in adequately powered clinical trials. FDA position to consider hemp-derived CBD as a drug only with prohibition to market it as a supplement appears as a legitimate safeguard against uncontrolled use of an active principal approved as a drug, which carries the risk of serious adverse events, drug—drug interaction, and cannot and should not be used without medical supervision.
Regulatory agencies are allowed to err on the side of prudence provided that sufficient impulse is given to the design and conduction of such clinical studies.
Prohibition of CBD marketing as a supplement ingredient within certain dose limits may limit consumers' right to have access to a naturally occurring substance obtained from THC-free hemp, which can be freely marketed. In contrast, interventions aimed at guaranteeing hemp-derived food safety are compulsory.
After analyzing the cannabinoid profile by a liquid chromatography method coupled to high-resolution mass spectrometry in 10 commercially available organic hempseed oils, Citti et al. The Zoo-Prophylactic Institute of Southern Italy IZSM is the first public Italian Institution operating under the supervision of the Italian Ministry of Health and with jurisdiction over food safety to provide assessment of THC content in food and hemp products in Accredia-certified internal laboratories, with enormous implications for public health and hemp law enforcement www.
This trial is going to prove or disprove safety of dietary hemp products and measure subsequent cannabinoid exposure in participating subjects. Hemp use in the food and supplement industry is predicted to expand in the coming years as demand grows, with enormous social, economic, and sanitary implications.
Legislative and regulatory interventions should aim at encouraging adequate clinical research to prove or disprove safety of hemp-derived products, which has not been done so far independently by the industry or by the scientific community. All authors equally contributed to literature search and critical revision for important intellectual content and finally approved the article.
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Forgot your username? Enter your email address below and we will send you your username. Search for more papers by this author. View article. References 1. Pollio A. The name of Cannabis : a short guide for nonbotanists. Cannabis Cannabinoid Res. Small E, Cronquist A. A practical and natural taxonomy for Cannabis.
Taxon ;— Pertwee R. Handbook of Cannabis. World Health Organization. Google Scholar 5. Cadena A. Hemp vs marijuana: the difference explained update. Google Scholar 6. Callaway JC.
Kama Hemp Juice capsules are a high-quality food supplement that is desired because it contains a broad range of nutrients. The extra potency of Kama Hemp. Hemp Products (e.g. CBD) in Food and Supplements. Legal Status. If you plan to sell hemp/CBD oil as a supplement or in a general food, you must consider that.
Hemp Cannabis sativa L. The various parts of the hemp plant are used to make different products. The seeds of hemp are edible and are considered highly nutritious with a high concentration of soluble and insoluble fiber, omega-3 and omega-6 fatty acids for heart health and skin health.
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Clearing up confusion about hemp supplements
As cannabis and hemp become more extensively researched and widely available, we are starting to realize the true therapeutic power of these plants and their derivatives. Today, we're clearing up the murkiness surrounding cannabis products, their differences, and the legality of taking them so we can focus on all the benefits of hemp oil extract as well as the ins and outs of buying and consuming it. There are many varietals of the Cannabis sativa plant , all of which contain different amounts of THC the psychoactive component , CBD a nonpsychoactive component , and other components. Cannabis sativa varietals that have more than 0. Hemp is any varietal of Cannabis sativa that contains less than 0. For a long time, researchers were only concerned with studying THC, the psychoactive component that is concentrated in marijuana.
A Review of Hemp As Food and Nutritional Supplement
Enter your email and we'll keep you on top of the latest nutrition research, supplement myths, and more. Our evidence-based analysis on hemp protein features 23 unique references to scientific papers. Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. The team includes nutrition researchers, registered dietitians, physicians, and pharmacists. We have a strict editorial process. This page features 23 references. All factual claims are followed by specifically-applicable references. Click here to see the full set of references for this page. Hemp protein is a industrial byproduct from hempseed where the seeds balanced macronutrient profile have their oil extracted into Hempseed oil, and the remainding seedmeal that is high in protein relative to the seeds is then processed into Hemp protein supplements. Hemp that is currently on the market is a strain low in THC the intoxicant and psychoactive agent in Marijuana and does not confer intoxicating properties.
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If you have questions, imagine the world for your patients. As their practitioner, you can reassure them and steer them in the right direction. First, you can assure them that supplemental hemp and marijuana are not the same thing. While Cannabis sativa is the source plant for both, differences between them are key.
