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Allow me to begin by clarifying a very important thing: I am not a pothead, a stoner, or a recreational drug enthusiast. Growing up, I was originally a fantasy fiction writing, World Of Warcraft dominating geek in my early years, and later in high school and college was a clean-living, well-shaven jock athlete with a substance abuse problem that consisted primarily of copious amounts of creatine, caffeine, and canned protein shakes. So there: now I'm a bonified druggie. In other words, you're going to learn about a form of cannabis with none of the psychoactive, paranoia-inducing effects of regular weed and all of the benefits.
CBD Bioavailability: What Does it Mean Why is it so Important?
Allow me to begin by clarifying a very important thing: I am not a pothead, a stoner, or a recreational drug enthusiast. Growing up, I was originally a fantasy fiction writing, World Of Warcraft dominating geek in my early years, and later in high school and college was a clean-living, well-shaven jock athlete with a substance abuse problem that consisted primarily of copious amounts of creatine, caffeine, and canned protein shakes.
So there: now I'm a bonified druggie. In other words, you're going to learn about a form of cannabis with none of the psychoactive, paranoia-inducing effects of regular weed and all of the benefits. So let's say you didn't grow up in the '60s, never had stoner parents, have lived a relatively clean life, or simply smoke joints without ever thinking too hard about what's happening chemically.
When people talk about marijuana or use marijuana, they're usually referring to tetrahydrocannabinol THC.
Or an annoying state, mildly schizophrenic state, depending on your perspective. We can at least say beyond a shadow of a doubt that it makes Family Guy episodes way, way funnier. So yes, it's true that we're not smoking the weed our parents smoked, and one draw on a typical joint these days would probably knock your mom on her ass.
We'll get into the most relevant of those medical applications later. And to understand this, you need to put on your straw hat and for the next 60 seconds become a hemp field farmer. But when the female is allowed to be pollinated, she barely produces any THC. Why on earth would you want to dump a bunch of CBD into your body with none of the fun, psychoactive properties of THC? Don't worry, we'll get to that.
There are some very, very good reasons. But first, it's important for you to understand what's going on inside your body when you consume this CBD stuff from those happily mating male and female plants. Head spinning? All this means is the following: all the things that would normally activate the CB1 or the CB2 receptors are turned off or turned down by CBD.
Place propeller hat on head. Which works just fine, by the way. But since its mechanism of action is not dependent on receptors associated with addiction, CBD is not addictive or habit-forming. So while the receptor explanation is conveniently simple, it's not quite accurate.
Don't worry, it probably wasn't as funny as you thought it was last night. Incidentally, that patent was not extended to actual oil or capsule extracts of cannabis, so the good ol' US gummint missed out on some pretty good business opportunities, if you ask me.
It's also nearly impossible to overdose on CBD. It's not like this stuff just popped up like Red Bull energy drinks, ecstasy, Lunesta, or Adderall. Hippocrates , the father of western medicine, also recommended cannabis extracts. Cannabis also has links to Christianity — specifically through the Ethiopian Coptic Church, which is held to have been established by St. The father of French psycho-pharmacology, Dr.
Anything that can be made of plastic can also be made from hemp, which can reduce exposure to phytoestrogens and other chemicals in plastic and other synthetic compounds. And of course, as you're probably aware, both THC and CBD seem to be immersed in a constant struggle of medical legality that I simply don't have the time to address in this post. Nonetheless, when it comes to CBD oil and cannabidiol, people seem be getting more aware of the fact that you don't need to be a pothead to get all the relaxing and hormone and metabolism-balancing properties of weed.
So, if CBD oil is so freaking magical, there must be a downside right? Addictive potential, perhaps? Toxicity and lack of proven safety? Although I touched on the absence of CB1 and CB2 receptor binding earlier in this article, let's delve into the addictive or unsafe potential of CBD just a bit more.
You already learned about the science behind that whole receptor thing. Now don't get me wrong — some will indeed claim that cannabis is addictive. For example, the Boggs Act of established mandatory sentences for drug users and also claimed that cannabis was addictive.
But Dr. In other words, if you're thirsty, this NIDA-funded research could argue that this means you are addicted to water. As a matter of fact, here's what this article reported about NIDA. As you can see, Dr. You can't find one. There are dozens of other doctors and similar studies, too many to list here — but you can certainly delve in at ProjectCBD website.
But when it comes to pain management, one of the primary uses for CBD oil , deaths from drug overdoses and drug poisoning continue to rise. Deaths from opioid analgesics — one of the most universally prescribed pain management drugs — increased from 4, in to 15, in and 16, in In , 60 percent of all drug overdose deaths 22, involved pharmaceutical drugs, and opioid analgesics showed up in about 3 of every 4 of those pharmaceutical overdose deaths.
That confirms the predominant role that research has shown opioid analgesics to play in drug-related mortality. And of course, as you already know, these benefits come without the proven addictive or unsafe nature of opioid drugs. I first talked about this video last year Is Weed Healthy? You get the idea, and now you probably also have a pretty good idea of why pharmaceutical companies would want to patent some chemical-ized version of this.
So, I'd suspect that we're not too far away from an enormously overpriced cannabis-like chemical produced in a pharmaceutical factory. But in the meantime, you can get the identical effects from entirely natural sources of CBD. Let's take a look at what some of those most relevant effects would be. Let's begin with your endocrine system and hormones. Here are the studies:. One major function of this system is to produce excitation in response to stress, which is of course necessary for survival, but when it gets out of hand it can be a source of excess stress.
CBD significantly decreases plasma cortisol levels , and this is actually why I started using CBD in the first place — to reduce my cortisol. But CBD has other effects on your endocrine system, particularly your appetite. You may simply think that marijuana produces the munchies and therefore makes you fat, and although this makes logical sense, science has shown that it's not the case that marijuana makes you fat, especially when CBD is present.
These hormones work as a pair to maintain homeostasis, and they stimulate the release of each other through a complex feedback mechanism. Type II diabetics whose pancreas still functions tend to have very high levels of insulin, but the liver is unable to use that insulin, so blood sugar stays high, and the pancreas eventually damages itself by trying to continually produce more and more insulin, eventually leading to organ failure if the diabetes is unmanaged. So the summary of the biggest effects of CBD on the endocrine system?
Lower cortisol and better blood sugar control. Let's move on. When it comes to stress, which is of course significantly related to anxiety, the host of studies are just as impressive:.
I've found that as little as 10mg CBD vastly lowers my anxiety at the end of the day, and have dosed with as high as mg CBD to be as calm as a baby during trans-Atlantic plane flights, nights sleeping in hotel rooms, and other situations where I have difficulty sleeping or tend to be stressed out.
The stuff works like a charm, and saves me from having to hunt down an unhealthy, addictive alternative like valium or diazepam. You can pretty much consider inflammation to be the freaking bane of our modern, fast-paced, industrialized lifestyles. For example, cytokines are the signaling proteins synthesized and secreted by immune cells upon stimulation. They are the modulating factors that balance initiation and resolution of inflammation.
Their findings were as follows:. The restoration of these interleukins to normal behavior by CBD, although the specific pathway is unknown, is another important therapeutic action that CBD has on reduction of colonic inflammation.
But from the joints to neural tissue, CBD has a variety of other natural anti-inflammatory effects. Here is just a smattering of the studies done on cannabidiols and inflammation. Many NFL athletes are now experimenting with cannabis extracts to manage post-head injury symptoms and to reduce the chronic mid and post-career aches and pains.
Bet you never thought you'd hear somebody recommending a weed derivative to lose weight, but it's true. Here is a great two-minute video that sums up how marijuana can help obesity and body fat:. In the United States, approximately 70 million people suffer from insomnia, insufficient sleep or another sleep disorder.
Cannabidiol actually activates the same adenosine receptors as caffeine, which is technically a stimulant. In summary: smaller doses of CBD provide you with a calm and relaxed focus that comes in handy during everything from writing to music to parties to workouts — very similar to what you would experience with THC, but without the psychoactive or paranoia properties.
OK, so there must be a catch here, because at this point you're probably under the impression that I think CBD is some kind of cure-all magical tonic that ranks right up there with Belgian chocolate, Bordeaux wine and kale smoothies. But problem is, CBD oil, capsules, powders, etc. They can spoil and become contaminated. They smell bad. They often taste bad too. Enter turmeric, the same flavorful spice that I mix with black pepper on my salads every single day of the year.
Turmeric comes from the rhizome in the turmeric plant, and the rhizome can grow up to 3 inches in length. Turmeric was a highly sought after commodity in the ancient spice trades that swept across China and Africa, all before the end of the 9th century.
For you aspiring fatty coffee drinkers out there, this is a similar concept to the idea that you simply never get to feel several of the bioactive, wakefulness and focus-enhancing terpenoids in coffee until you have actually introduced fats and triglycerides into the coffee to help these terpenes cross your blood-brain barrier — hence the butter and coconut oil blended with the coffee. The way that hybrid-nanoengineering works is that the cannabinoids and terpenoids are extracted from the hemp plant, combined with an Ayurvedic herbal blend and then processed into nanoparticle size.
The oil is then encapsulated, and…. Here's a video that demonstrates the absorption difference between water soluble CBD that's been hybrid-nanoengineered, compared to regular, non-water-soluble CBD. The resulting oil then is strictly tested for purity and is free from pesticides and heavy metals.
For example, in validated models of anxiety and depression, ashwagandha has been demonstrated to be as effective as some tranquilizers and antidepressant drugs.
Stress can cause increased peroxidation of lipids, while decreasing levels of the antioxidant enzymes catalase and glutathione peroxidase. It is this type of cellular degeneration that can lead to long-term cognitive difficulties.
In one of the most complete human clinical trials to date , researchers studied the effects of a standardized extract of ashwagandha on the negative effects of stress, including elevated levels of the stress hormone cortisol.
Infused with cannabis sativa seed oil, green tea extract, chamomile and Get baked and bronzed with the first luxurious CBD-infused tanning mousse. Tone Down spray, $29 at Fitish along with CBD and tart cherry powder, the powders promise to optimize relaxation and ease sore and achy joints. Buy (2-Pack) Hemp Oil Spray - mg - Faster Absorption - Natural Berry & Mint Hemp Gummies - Zero THC CBD Oil Cannabidiol - MG - 35 MG per.
By Bree Bonagofsky. April 20, am Updated April 22, am. Besides their scintillating aroma, CBD cannabidiol products promise to reduce inflammation, calm nerves and alleviate pain. While few of these benefits are backed up by medical studies, the cannabis craze shows no signs of slowing down. From CBD-infused oils and eye masks to gummies and skin-care potions, chill out with our favorite plant-based picks.
Although few studies have been carried out, the small amount of available studies are promising. Quinones occur in nature and occur after oxidation of the polyphenols present in plants.
Not all CBD is the same. Discover the differences between CBD delivery forms and the pros and cons of each. Learn how to choose the best CBD form for you.
Get All The Health Benefits Of Smoking Weed Without Actually Smoking Weed.
Looking for a quick and easy way to get the THC you need? Skip the smoke and go straight for the pill. THC pills, that is. Did you know you can get all the high-flying, fall-off-the-floor, who-are-the-Grateful-Dead-and-why-are-they-following-me goodness that you expect from your doobies in a convenient little pill? We know. Mind blown, right?
THC Pills: Your Guide To The Healthiest Chill Pills
Consumed by adults all around the world, Plus CBD Oil is trusted to deliver the purest, consistent and traceable cannabinoids in North America. Made with cannabidiol derived from agricultural hemp, Plus CBD Oil capsules help you to optimize your human potential. Supplement Facts 1 capsule contains: Hemp Oil Aerial Plant Parts mg Cannabidiol CBD 15mg Other Ingredients: food starch - modified, vegetable cellulose, silicon dioxide, vegetarian capsule vegetable cellulose, water , magnesium stearate. Recommended Use: Adults: As a dietary supplement, take 1 capsule. This product is a temperature-sensitive item and is kept refrigerated. When you order a refrigerated item, we offer a variety of options to help keep your purchase cool longer during shipping. To avoid the risk of having this sensitive item stuck somewhere over a weekend, it will be shipped on a Monday or Tuesday. Choose an expedited shipping option with included cooler and ice pack if it's very important to you that your refrigerated item gets to you still cool or if you would like it shipped anytime during the week instead of just a Monday or Tuesday. You may also purchase an add-on ice pack to be included in your shipment from the cart page during checkout. Get what you need from Natural Healthy Concepts exactly when you need it and earn bonus rewards points.
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Cannabidiol CBD is a nonpsychoactive phytocannabinoid used in multiple sclerosis and intractable epilepsies. Preclinical studies show CBD has numerous cardiovascular benefits, including a reduced blood pressure BP response to stress. Nine healthy male volunteers were given mg of CBD or placebo in a randomized, placebo-controlled, double-blind, crossover study. Cardiovascular parameters were monitored using a finometer and laser Doppler. These hemodynamic changes should be considered for people taking CBD. Further research is required to establish whether CBD has a role in the treatment of cardiovascular disorders. Epidemiological studies have shown a positive relationship between long-term stress and the development of cardiovascular disease 1. Factors like social isolation, low socioeconomic status, depression, stressful family and work life, and anxiety are associated with an increased risk of the development and accelerated progression of existing cardiovascular disease. Current European guidelines on the prevention of cardiovascular disease have emphasized the importance of tackling these factors 2. Mental stress induces myocardial ischaemia in patients with stable coronary artery disease, and this appears to be mediated by adrenal release of catecholamines 3. Cannabinoids CBs are compounds that bind to CB receptors or are structurally similar to compounds that bind to CB receptors. They include endogenously produced compounds called endocannabinoids , synthetic compounds and phytocannabinoids obtained from the Cannabis sativa plant. The other major phytocannabinoid is cannabidiol CBD , which does not have psychoactive properties. CBD is currently the focus of much research due to its potential in a number of therapeutic areas, as it has been shown to have antiinflammatory, anticonvulsant, antioxidant, anxiolytic, antinausea, and antipsychotic properties 5.
The best CBD products to buy in honor of 4/20
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